Ribonuclease MRP protein subunit p24 (RMP24)

About Ribonuclease MRP protein subunit p24

Ribonuclease MRP protein subunit p24 (RMP24) is a protein from Homo sapiens identified by UniProt accession Q32NC0, 220 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Ribonuclease MRP protein subunit p24
UniProt accession	Q32NC0
Gene	RMP24
Organism	Homo sapiens
Length	220 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

mean corpuscular volume · score 0.37
neurodegenerative disease · score 0.33
mean corpuscular hemoglobin concentration · score 0.32
mean corpuscular hemoglobin · score 0.23
protein measurement · score 0.03
eosinophilic esophagitis · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q32NC0-F1	alphafold	PREDICTED	74.04	—

Amino-acid sequence (220 residues)

MRQKHYLEAA ARGLHDSCPG QARYLLWAYT SSHDDKSTFE ETCPYCFQLL VLDNSRVRLK PKARLTPKIQ KLLNREARNY TLSFKEAKMV KKFKDSKSVL LITCKTCNRT VKHHGKSRSF VSTLKSNPAT PTSKLSLKTP ERRTANPNHD MSGSKGKSPA SVFRTPTSGQ SVSTCSSKNT SKTKKHFSQL KMLLSQNESQ KIPKVDFRNF LSSLKGGLLK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards