About Protein FAM161A
Protein FAM161A (FAM161A) is a protein
from Homo sapiens identified by UniProt accession
Q3B820, 660 residues long.
MolForge cross-references it against 0 known binders and
48 disease associations.
Target properties
| Protein name | Protein FAM161A |
|---|
| UniProt accession | Q3B820 |
|---|
| Gene | FAM161A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 660 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (48)
Diseases linked to this target (Open Targets).
- retinitis pigmentosa · score 0.78
- Retinal dystrophy · score 0.53
- autosomal recessive retinitis pigmentosa · score 0.46
- neurodegenerative disease · score 0.42
- genetic disorder · score 0.41
- Posterior column ataxia - retinitis pigmentosa · score 0.41
- Cone rod dystrophy · score 0.33
- cone-rod dystrophy · score 0.33
- mean corpuscular volume · score 0.26
- protein measurement · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q3B820-F1 | alphafold | PREDICTED | 66.36 | — |
Amino-acid sequence (660 residues)
MATSHRVAKL VASSLQTPVN PITGARVAQY EREDPLKALA AAEAILEDEE EEKVAQPAGA SADLNTSFSG VDEHAPISYE DFVNFPDIHH SNEEYFKKVE ELKAAHIETM AKLEKMYQDK LHLKEVQPVV IREDSLSDSS RSVSEKNSYH PVSLMTSFSE PDLGQSSSLY VSSSEEELPN LEKEYPRKNR MMTYAKELIN NMWTDFCVED YIRCKDTGFH AAEKRRKKRK EWVPTITVPE PFQMMIREQK KKEESMKSKS DIEMVHKALK KQEEDPEYKK KFRANPVPAS VFLPLYHDLV KQKEERRRSL KEKSKEALLA SQKPFKFIAR EEQKRAAREK QLRDFLKYKK KTNRFKARPI PRSTYGSTTN DKLKEEELYR NLRTQLRAQE HLQNSSPLPC RSACGCRNPR CPEQAVKLKC KHKVRCPTPD FEDLPERYQK HLSEHKSPKL LTVCKPFDLH ASPHASIKRE KILADIEADE ENLKETRWPY LSPRRKSPVR CAGVNPVPCN CNPPVPTVSS RGREQAVRKS EKERMREYQR ELEEREEKLK KRPLLFERVA QKNARMAAEK HYSNTLKALG ISDEFVSKKG QSGKVLEYFN NQETKSVTED KESFNEEEKI EERENGEENY FIDTNSQDSY KEKDEANEES EEEKSVEESH
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