About Ankyrin repeat domain-containing protein 55
Ankyrin repeat domain-containing protein 55 (ANKRD55) is a protein
from Homo sapiens identified by UniProt accession
Q3KP44, 614 residues long.
MolForge cross-references it against 0 known binders and
146 disease associations.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 55 |
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| UniProt accession | Q3KP44 |
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| Gene | ANKRD55 |
|---|
| Organism | Homo sapiens |
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| Length | 614 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (146)
Diseases linked to this target (Open Targets).
- rheumatoid arthritis · score 0.54
- monocyte count · score 0.49
- Crohn's disease · score 0.49
- multiple sclerosis · score 0.46
- erythrocyte count · score 0.46
- monocyte percentage of leukocytes · score 0.45
- reticulocyte count · score 0.44
- urate measurement · score 0.43
- total blood protein measurement · score 0.42
- type 1 diabetes mellitus · score 0.42
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q3KP44-F1 | alphafold | PREDICTED | 64.24 | — |
Amino-acid sequence (614 residues)
MMRQATMDFS TPSVFDQQRG DSSEEVDLTM VYQAASNGDV NALTAVIRED PSILECCDSE GCTPLMHAVS GRQADTVKLL LKMGANINMQ DAYGRTSLCL ATYLGWLEGC VSLLRNGAKH NIPDKNGRLP LHAATAEPDM RLLTVLLQQS NISEINHQDN EGMTPLHWAA FHNQPQHTQM LLKKGADPTL VDKDFKTALH WAVQSGNRIL CSIILSHHQG PSIINYDDES GKTCVHIAAA AGFSDIIHEL ARVPECNLQA LDVDDRTPLH WAAAAGKAEC VQSLLELGMD SNLRDINEST PLAYALYCGH TACVKLLSQE SRTEPTRPPP SQSSRPQKKE RRFNVLNQIF CKNKKEEQRA HQKDPSRDRY REEDTSEVND IITTFDSIVG TNCQEQPGDQ VAMVEFKKKT SDNSKYLLPE KKPLARKGLP PIRTQSLPPI TLGNNFLTAS HRATSHAGLS SAPHHMAQRS QKSRSEQDLL NNRTGCQMLL DNPWKSDSNQ VFSYKVWTVS SSDKLLDRLL SVRPGHQEVS VPPHLRHLHN PSSGQNFQHL SPNRHKIRDL PFTRNNLAPL PDQKFLSGEP LRTNRVLPAI PSQRRHSTAA EESEHSANPT SDEN
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