Cell adhesion molecule CEACAM21 (CEACAM21)

About Cell adhesion molecule CEACAM21

Cell adhesion molecule CEACAM21 (CEACAM21) is a protein from Homo sapiens identified by UniProt accession Q3KPI0, 293 residues long. MolForge cross-references it against 0 known binders and 137 disease associations.

Target properties

Protein name	Cell adhesion molecule CEACAM21
UniProt accession	Q3KPI0
Gene	CEACAM21
Organism	Homo sapiens
Length	293 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (137)

Diseases linked to this target (Open Targets).

ringed hair disease · score 0.08
Griscelli syndrome type 3 · score 0.08
uncombable hair syndrome · score 0.08
MODY · score 0.07
Blackfan-Diamond anemia · score 0.07
testosterone measurement · score 0.07
hyperproinsulinemia · score 0.07
hyperinsulinism due to INSR deficiency · score 0.07
hypertriglyceridemia 2 · score 0.07
Gorham-Stout disease · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3KPI0-F1	alphafold	PREDICTED	85.18	—

Amino-acid sequence (293 residues)

MGPPSACPHR ECIPWQGLLL TASLLTFWNA PTTAWLFIAS APFEVAEGEN VHLSVVYLPE NLYSYGWYKG KTVEPNQLIA AYVIDTHVRT PGPAYSGRET ISPSGDLHFQ NVTLEDTGYY NLQVTYRNSQ IEQASHHLRV YESVAQPSIQ ASSTTVTEKG SVVLTCHTNN TGTSFQWIFN NQRLQVTKRM KLSWFNHVLT IDPIRQEDAG EYQCEVSNPV SSNRSDPLKL TVKSDDNTLG ILIGVLVGSL LVAALVCFLL LRKTGRASDQ SDFREQQPPA STPGHGPSDS SIS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards