About MAP7 domain-containing protein 1
MAP7 domain-containing protein 1 (MAP7D1) is a protein
from Homo sapiens identified by UniProt accession
Q3KQU3, 841 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | MAP7 domain-containing protein 1 |
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| UniProt accession | Q3KQU3 |
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| Gene | MAP7D1 |
|---|
| Organism | Homo sapiens |
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| Length | 841 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (30)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- lean body mass · score 0.27
- body weight · score 0.24
- PR interval · score 0.22
- base metabolic rate measurement · score 0.18
- fat body mass · score 0.16
- whole body water mass · score 0.06
- attention deficit hyperactivity disorder · score 0.06
- Tourette syndrome · score 0.05
- schizophrenia 15 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q3KQU3-F1 | alphafold | PREDICTED | 58.44 | — |
Amino-acid sequence (841 residues)
MESGPRAELG AGAPPAVVAR TPPEPRPSPE GDPSPPPPPM SALVPDTPPD TPPAMKNATS SKQLPLEPES PSGQVGPRPA PPQEESPSSE AKSRGPTPPA MGPRDARPPR RSSQPSPTAV PASDSPPTKQ EVKKAGERHK LAKERREERA KYLAAKKAVW LEKEEKAKAL REKQLQERRR RLEEQRLKAE QRRAALEERQ RQKLEKNKER YEAAIQRSVK KTWAEIRQQR WSWAGALHHS SPGHKTSGSR CSVSAVNLPK HVDSIINKRL SKSSATLWNS PSRNRSLQLS AWESSIVDRL MTPTLSFLAR SRSAVTLPRN GRDQGRGCDP GRGPTWGRAG ASLARGPQPD RTHPSAAVPV CPRSASASPL TPCSVTRSVH RCAPAGERGE RRKPNAGGSP APVRRRPEAS PVQKKEKKDK ERENEKEKSA LARERSLKKR QSLPASPRAR LSASTASELS PKSKARPSSP STSWHRPASP CPSPGPGHTL PPKPPSPRGT TASPKGRVRR KEEAKESPSA AGPEDKSQSK RRASNEKESA APASPAPSPA PSPTPAPPQK EQPPAETPTD AAVLTSPPAP APPVTPSKPM AGTTDREEAT RLLAEKRRQA REQREREEQE RRLQAERDKR MREEQLAREA EARAEREAEA RRREEQEARE KAQAEQEEQE RLQKQKEEAE ARSREEAERQ RLEREKHFQQ QEQERQERRK RLEEIMKRTR KSEVSETKQK QDSKEANANG SSPEPVKAVE ARSPGLQKEA VQKEEPIPQE PQWSLPSKEL PASLVNGLQP LPAHQENGFS TNGPSGDKSL SRTPETLLPF AEAEAFLKKA VVQSPQVTEV L
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