Keratin-associated protein 21-1 (KRTAP21-1)

About Keratin-associated protein 21-1

Keratin-associated protein 21-1 (KRTAP21-1) is a protein from Homo sapiens identified by UniProt accession Q3LI58, 79 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.

Target properties

Protein name	Keratin-associated protein 21-1
UniProt accession	Q3LI58
Gene	KRTAP21-1
Organism	Homo sapiens
Length	79 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (2)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.18
diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3LI58-F1	alphafold	PREDICTED	46.44	—

Amino-acid sequence (79 residues)

MCCNYYGNSC GYGSGCGCGY GSGSGCGCGY GTGYGCGYGC GFGSHYGCGY GTGYGCGYGS GSGYCGYRPF CFRRCYSSC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards