Keratin-associated protein 21-2 (KRTAP21-2)

About Keratin-associated protein 21-2

Keratin-associated protein 21-2 (KRTAP21-2) is a protein from Homo sapiens identified by UniProt accession Q3LI59, 83 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.

Target properties

Protein name	Keratin-associated protein 21-2
UniProt accession	Q3LI59
Gene	KRTAP21-2
Organism	Homo sapiens
Length	83 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (3)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.18
low grade glioma · score 0.11
gastric carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3LI59-F1	alphafold	PREDICTED	34.95	—

Amino-acid sequence (83 residues)

MCCNYYRNCC GGCGYGSGWS SGCGYGCGYG CGYGSGCRYG SGYGTGCGYG CGYGSGCGYG CGYSSSCCGY RPLCYRRCYS SCY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards