Keratin-associated protein 6-1 (KRTAP6-1)

About Keratin-associated protein 6-1

Keratin-associated protein 6-1 (KRTAP6-1) is a protein from Homo sapiens identified by UniProt accession Q3LI64, 71 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	Keratin-associated protein 6-1
UniProt accession	Q3LI64
Gene	KRTAP6-1
Organism	Homo sapiens
Length	71 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.26
head and neck squamous cell carcinoma · score 0.18
glioblastoma multiforme · score 0.18
breast adenocarcinoma · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3LI64-F1	alphafold	PREDICTED	43.06	—

Amino-acid sequence (71 residues)

MCGSYYGNYY GTPGYGFCGY GGLGYGYGGL GCGYGSCCGC GFRRLGCGYG YGSRSLCGYG YGCGSGSGYY Y

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards