Keratin-associated protein 6-2 (KRTAP6-2)

About Keratin-associated protein 6-2

Keratin-associated protein 6-2 (KRTAP6-2) is a protein from Homo sapiens identified by UniProt accession Q3LI66, 62 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	Keratin-associated protein 6-2
UniProt accession	Q3LI66
Gene	KRTAP6-2
Organism	Homo sapiens
Length	62 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.18
prostate adenocarcinoma · score 0.18
thyroid gland adenocarcinoma · score 0.16
smoking status measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3LI66-F1	alphafold	PREDICTED	42.22	—

Amino-acid sequence (62 residues)

MCGSYYGNYY GDHGYGCCGY EGLGYGYGSL RCGYSSCCGY GHGYGSRFFC GCGYGCGSGY YY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards