Keratin-associated protein 13-4 (KRTAP13-4)

About Keratin-associated protein 13-4

Keratin-associated protein 13-4 (KRTAP13-4) is a protein from Homo sapiens identified by UniProt accession Q3LI77, 160 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Keratin-associated protein 13-4
UniProt accession	Q3LI77
Gene	KRTAP13-4
Organism	Homo sapiens
Length	160 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.31
head and neck squamous cell carcinoma · score 0.18
clear cell renal carcinoma · score 0.18
prostate adenocarcinoma · score 0.18
breast adenocarcinoma · score 0.18
gastric carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3LI77-F1	alphafold	PREDICTED	43.60	—

Amino-acid sequence (160 residues)

MSYNCCSRNF SSRSFGGYLY YPGSYPSSLV YSTALCSPST CQLRSSLYRD CQKTCWEPAS CQKSCYRPRT SILCCPCQTT CSGSLGFRSS SCRSQGYGSR CCYSLGNGSS GFRFLKYGGC GFPSLSYGSR FCYPNYLASG AWQSSCYRPI CGSRFYQFTC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards