Keratin-associated protein 27-1 (KRTAP27-1)

About Keratin-associated protein 27-1

Keratin-associated protein 27-1 (KRTAP27-1) is a protein from Homo sapiens identified by UniProt accession Q3LI81, 207 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Keratin-associated protein 27-1
UniProt accession	Q3LI81
Gene	KRTAP27-1
Organism	Homo sapiens
Length	207 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.18
ovarian cancer · score 0.18
breast adenocarcinoma · score 0.18
thyroid gland adenocarcinoma · score 0.16
gastric carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3LI81-F1	alphafold	PREDICTED	51.56	—

Amino-acid sequence (207 residues)

MPHSHCHSLR SFHNAPPLSA ITHGTNPITF EDRLCLPSSF HSRTCFLDNF QETCNETTSC QMTNCEQDLF TDDSCVQSNC FPGVVQTTYS NSRPCERTAC QSESSSAGLA CVSQPCQSES TQQMGFVAQS CQPASLKGNS CPPKTSKSKN FETLERASSQ CQCQSQNPES SSCRPLVNVA PEPQLLESSP GVEPTCCVTG GSQLPSK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards