Keratin-associated protein 24-1 (KRTAP24-1)

About Keratin-associated protein 24-1

Keratin-associated protein 24-1 (KRTAP24-1) is a protein from Homo sapiens identified by UniProt accession Q3LI83, 254 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Keratin-associated protein 24-1
UniProt accession	Q3LI83
Gene	KRTAP24-1
Organism	Homo sapiens
Length	254 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.18
breast adenocarcinoma · score 0.18
esophageal cancer · score 0.14
smoking status measurement · score 0.02
cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3LI83-F1	alphafold	PREDICTED	40.53	—

Amino-acid sequence (254 residues)

MPAGSMSTTG YPGVCSTTSY RTHCYIPVTS SVTLSSSDLS PTFGHCLPSS YQGNLWLLDY CQESYGEAPT CKSPSCEPKT CSTTGCDPSN SSVPCNSPSA GQVFSVCETT NVSPSPSCSP STQTNGYVCN CHIPTRNASK ACQTLRNGSN CFGQLNCLSK SFQTLNHCRL STLGYKSYQN PCFIPSYVSP LCYISNSCQP QSYLVRNYHY SSYRPTSCRP LSYLSRSFRS LSYIPSTFPP LRYLCSGSRP LKCY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards