Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y (PIGY)

About Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y

Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y (PIGY) is a protein from Homo sapiens identified by UniProt accession Q3MUY2, 71 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

Target properties

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Disease associations (24)

Diseases linked to this target (Open Targets).

• neurodegenerative disease · score 0.55
• hyperphosphatasia-intellectual disability syndrome · score 0.53
• hypercoagulability syndrome due to glycosylphosphatidylinositol deficiency · score 0.37
• lysosomal storage disease · score 0.37
• mitochondrial disease · score 0.33
• urate measurement · score 0.15
• handedness · score 0.03
• mean platelet volume · score 0.02
• FEV/FVC ratio · score 0.02
• renal system measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Amino-acid sequence (71 residues)

External references