About Inactive hydroxysteroid dehydrogenase-like protein 1
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) is a protein
from Homo sapiens identified by UniProt accession
Q3SXM5, 330 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Inactive hydroxysteroid dehydrogenase-like protein 1 |
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| UniProt accession | Q3SXM5 |
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| Gene | HSDL1 |
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| Organism | Homo sapiens |
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| Length | 330 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (7)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- mathematical ability · score 0.24
- self reported educational attainment · score 0.24
- primary ciliary dyskinesia · score 0.16
- gut microbiome measurement · score 0.08
- COVID-19 · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q3SXM5-F1 | alphafold | PREDICTED | 92.37 | — |
Amino-acid sequence (330 residues)
MAAVDSFYLL YREIARSCNC YMEALALVGA WYTARKSITV ICDFYSLIRL HFIPRLGSRA DLIKQYGRWA VVSGATDGIG KAYAEELASR GLNIILISRN EEKLQVVAKD IADTYKVETD IIVADFSSGR EIYLPIREAL KDKDVGILVN NVGVFYPYPQ YFTQLSEDKL WDIINVNIAA ASLMVHVVLP GMVERKKGAI VTISSGSCCK PTPQLAAFSA SKAYLDHFSR ALQYEYASKG IFVQSLIPFY VATSMTAPSN FLHRCSWLVP SPKVYAHHAV STLGISKRTT GYWSHSIQFL FAQYMPEWLW VWGANILNRS LRKEALSCTA
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