About Protein shisa-like-1
Protein shisa-like-1 (SHISAL1) is a protein
from Homo sapiens identified by UniProt accession
Q3SXP7, 199 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Protein shisa-like-1 |
|---|
| UniProt accession | Q3SXP7 |
|---|
| Gene | SHISAL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 199 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (24)
Diseases linked to this target (Open Targets).
- Abnormality of the tongue · score 0.26
- Senior-Boichis syndrome · score 0.04
- Barrett's esophagus · score 0.04
- glioblastoma multiforme · score 0.04
- hepatorenocardiac degenerative fibrosis · score 0.03
- nephronophthisis · score 0.03
- sclerosing cholangitis · score 0.03
- gallbladder disease · score 0.03
- colorectal cancer · score 0.03
- astrocytoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q3SXP7-F1 | alphafold | PREDICTED | 67.19 | — |
Amino-acid sequence (199 residues)
MTSCGQQSLN VLAVLFSLLF SAVLSAHFRV CEPYTDHKGR YHFGFHCPRL SDNKTFILCC HHNNTVFKYC CNETEFQAVM QANLTASSEG YMHNNYTALL GVWIYGFFVL MLLVLDLLYY SAMNYDICKV YLARWGIQGR WMKQDPRRWG NPARAPRPGQ RAPQPQPPPG PLPQAPQAVH TLRGDAHSPP LMTFQSSSA
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