About Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A52
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A52 (SLC25A52) is a protein
from Homo sapiens identified by UniProt accession
Q3SY17, 297 residues long.
MolForge cross-references it against 0 known binders and
6 disease associations.
Target properties
| Protein name | Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A52 |
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| UniProt accession | Q3SY17 |
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| Gene | SLC25A52 |
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| Organism | Homo sapiens |
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| Length | 297 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (6)
Diseases linked to this target (Open Targets).
- metabolite measurement · score 0.05
- colorectal adenocarcinoma · score 0.04
- TNF-related apoptosis-inducing ligand measurement · score 0.03
- blood protein measurement · score 0.02
- thyroxine measurement · score 0.02
- non-small cell lung carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q3SY17-F1 | alphafold | PREDICTED | 80.74 | — |
Amino-acid sequence (297 residues)
MIDSEAHEKR PPILTSSKQD ISPHITNVGE MKHYLCGCCA AFNNVAITYP IQKVLFRQQL YGIKTRDAVL QLRRDGFRNL YRGILPPLMQ KTTTLALMFG LYEDLSCLLR KHVRAPEFAT HGVAAVLAGT AEAIFTPLER VQTLLQNHKH HDKFTNTYQA FKALKCHGIG EYYRGLVPIL FRNGLSNVLF FGLRGPIKEH LPTATTHSAH LVNDFIGGGL LGAMLGFLCF PINVVKTRLQ SQIGGEFQSF PKVFQKIWLE RDRKLINLFR GAHLNYHRSL ISWGIINATY EFLLKFI
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