Keratin-associated protein 13-3 (KRTAP13-3)

About Keratin-associated protein 13-3

Keratin-associated protein 13-3 (KRTAP13-3) is a protein from Homo sapiens identified by UniProt accession Q3SY46, 172 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Keratin-associated protein 13-3
UniProt accession	Q3SY46
Gene	KRTAP13-3
Organism	Homo sapiens
Length	172 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.30
head and neck squamous cell carcinoma · score 0.18
prostate adenocarcinoma · score 0.18
ovarian cancer · score 0.18
breast adenocarcinoma · score 0.18
esophageal cancer · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3SY46-F1	alphafold	PREDICTED	44.79	—

Amino-acid sequence (172 residues)

MSYNCCSRNF SSCSHGGYLH YPGSSCGSSY PSNLVYSTDL CSPSTCQLGS SLYRGCQETC WRPNSCQTLC VESSPCHTSC YYPRTHMLCN SCLTMHVGSR GFGSNSCCSL SCGSRSCSSL GCGSNGFRYL NYRIHTSPSQ SYRSRFCHPI YFPPRRWFHS SCYQPFCRSG FY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards