About UDP-glucuronosyltransferase 3A2
UDP-glucuronosyltransferase 3A2 (UGT3A2) is a protein
from Homo sapiens identified by UniProt accession
Q3SY77, 523 residues long.
MolForge cross-references it against 0 known binders and
27 disease associations.
Target properties
| Protein name | UDP-glucuronosyltransferase 3A2 |
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| UniProt accession | Q3SY77 |
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| Gene | UGT3A2 |
|---|
| Organism | Homo sapiens |
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| Length | 523 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (27)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.29
- type 2 diabetes mellitus · score 0.21
- cutaneous melanoma · score 0.18
- lung adenocarcinoma · score 0.17
- glioblastoma multiforme · score 0.17
- squamous cell lung carcinoma · score 0.10
- lean body mass · score 0.10
- base metabolic rate measurement · score 0.09
- serum non-albumin protein measurement · score 0.06
- eosinophil percentage of leukocytes · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q3SY77-F1 | alphafold | PREDICTED | 90.67 | — |
Amino-acid sequence (523 residues)
MAGQRVLLLV GFLLPGVLLS EAAKILTIST VGGSHYLLMD RVSQILQDHG HNVTMLNHKR GPFMPDFKKE EKSYQVISWL APEDHQREFK KSFDFFLEET LGGRGKFENL LNVLEYLALQ CSHFLNRKDI MDSLKNENFD MVIVETFDYC PFLIAEKLGK PFVAILSTSF GSLEFGLPIP LSYVPVFRSL LTDHMDFWGR VKNFLMFFSF CRRQQHMQST FDNTIKEHFT EGSRPVLSHL LLKAELWFIN SDFAFDFARP LLPNTVYVGG LMEKPIKPVP QDLENFIAKF GDSGFVLVTL GSMVNTCQNP EIFKEMNNAF AHLPQGVIWK CQCSHWPKDV HLAANVKIVD WLPQSDLLAH PSIRLFVTHG GQNSIMEAIQ HGVPMVGIPL FGDQPENMVR VEAKKFGVSI QLKKLKAETL ALKMKQIMED KRYKSAAVAA SVILRSHPLS PTQRLVGWID HVLQTGGATH LKPYVFQQPW HEQYLLDVFV FLLGLTLGTL WLCGKLLGMA VWWLRGARKV KET
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