About Annexin-2 receptor
Annexin-2 receptor (ANXA2R) is a protein
from Homo sapiens identified by UniProt accession
Q3ZCQ2, 193 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | Annexin-2 receptor |
|---|
| UniProt accession | Q3ZCQ2 |
|---|
| Gene | ANXA2R |
|---|
| Organism | Homo sapiens |
|---|
| Length | 193 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (28)
Diseases linked to this target (Open Targets).
- DNA methylation · score 0.13
- insulin like growth factor measurement · score 0.08
- metabolite measurement · score 0.04
- self reported educational attainment · score 0.03
- hepatocellular carcinoma · score 0.03
- body height · score 0.03
- Cannabis use · score 0.02
- attention deficit hyperactivity disorder · score 0.02
- Miyoshi myopathy · score 0.02
- renal cell carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q3ZCQ2-F1 | alphafold | PREDICTED | 55.72 | — |
Amino-acid sequence (193 residues)
MEQHFLGCVK RAWDSAEVAP EPQPPPIVSS EDRGPWPLPL YPVLGEYSLD SCDLGLLSSP CWRLPGVYWQ NGLSPGVQST LEPSTAKPTE FSWPGTQKQQ EAPVEEVGQA EEPDRLRLQQ LPWSSPLHPW DRQQDTEVCD SGCLLERRHP PALQPWRHLP GFSDCLEWIL RVGFAAFSVL WACCSRICGA KQP
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