Zinc finger protein 260 (ZNF260)

About Zinc finger protein 260

Zinc finger protein 260 (ZNF260) is a protein from Homo sapiens identified by UniProt accession Q3ZCT1, 412 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.

Target properties

Protein name	Zinc finger protein 260
UniProt accession	Q3ZCT1
Gene	ZNF260
Organism	Homo sapiens
Length	412 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (45)

Diseases linked to this target (Open Targets).

glomerular filtration rate · score 0.33
neuroinflammatory disorder · score 0.29
neurodegenerative disease · score 0.26
Lipedema · score 0.05
Milroy disease · score 0.05
mean corpuscular volume · score 0.04
nephrotic syndrome · score 0.04
lymphatic malformation 8 · score 0.04
Eiken syndrome · score 0.04
fibular hemimelia · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3ZCT1-F1	alphafold	PREDICTED	82.03	—

Amino-acid sequence (412 residues)

MIGMLESLQH ESDLLQHDQI HTGEKPYECN ECRKTFSLKQ NLVEHKKMHT GEKSHECTEC GKVCSRVSSL TLHLRSHTGK KAYKCNKCGK AFSQKENFLS HQKHHTGEKP YECEKVSIQM PTIIRHQKNH TGTKPYACKE CGKAFNGKAY LTEHEKIHTG EKPFECNQCG RAFSQKQYLI KHQNIHTGKK PFKCSECGKA FSQKENLIIH QRIHTGEKPY ECKGCGKAFI QKSSLIRHQR SHTGEKPYTC KECGKAFSGK SNLTEHEKIH IGEKPYKCNE CGTIFRQKQY LIKHHNIHTG EKPYECNKCG KAFSRITSLI VHVRIHTGDK PYECKVCGKA FCQSSSLTVH MRSHTGEKPY GCNECGKAFS QFSTLALHMR IHTGEKPYQC SECGKAFSQK SHHIRHQRIH TH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards