Galectin-related protein (LGALSL)

About Galectin-related protein

Galectin-related protein (LGALSL) is a protein from Homo sapiens identified by UniProt accession Q3ZCW2, 172 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.

Target properties

Protein name	Galectin-related protein
UniProt accession	Q3ZCW2
Gene	LGALSL
Organism	Homo sapiens
Length	172 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (36)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.43
mathematical ability · score 0.25
body height · score 0.24
neoplasm · score 0.03
drug use measurement · score 0.02
lung adenocarcinoma · score 0.02
cancer · score 0.01
lipoid nephrosis · score 0.01
nephrosis · score 0.01
juvenile dermatomyositis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q3ZCW2-F1	alphafold	PREDICTED	86.65	—

Amino-acid sequence (172 residues)

MAGSVADSDA VVKLDDGHLN NSLSSPVQAD VYFPRLIVPF CGHIKGGMRP GKKVLVMGIV DLNPESFAIS LTCGDSEDPP ADVAIELKAV FTDRQLLRNS CISGERGEEQ SAIPYFPFIP DQPFRVEILC EHPRFRVFVD GHQLFDFYHR IQTLSAIDTI KINGDLQITK LG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards