About Zinc finger protein 568
Zinc finger protein 568 (ZNF568) is a protein
from Homo sapiens identified by UniProt accession
Q3ZCX4, 644 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Zinc finger protein 568 |
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| UniProt accession | Q3ZCX4 |
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| Gene | ZNF568 |
|---|
| Organism | Homo sapiens |
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| Length | 644 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (29)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.22
- eosinophil count · score 0.17
- gait measurement · score 0.12
- insomnia · score 0.11
- eosinophil percentage of leukocytes · score 0.10
- insomnia measurement · score 0.09
- platelet crit · score 0.07
- sitting height measurement · score 0.07
- BMI-adjusted hip circumference · score 0.07
- appendicular lean mass · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q3ZCX4-F1 | alphafold | PREDICTED | 74.01 | — |
Amino-acid sequence (644 residues)
MTSQSSVISN SCVTMERLSH MMERKAWCSQ ESALSEEEED TTRPLETVTF KDVAVDLTQE EWEQMKPAQR NLYRDVMLEN YSNLVTVGCQ VTKPDVIFKL EQEEEPWVME EEMFGRHCPE VWEVDEQIKK QQETLVRKVT SISKKILIKE KVIECKKVAK IFPLSSDIVT SRQSFYDCDS LDKGLEHNLD LLRYEKGCVR EKQSNEFGKP FYHCASYVVT PFKCNQCGQD FSHKFDLIRH ERIHAGEKPY ECKECGKAFS RKENLITHQK IHTGEKPYKC NECGKAFIQM SNLIRHHRIH TGEKPYACKD CWKAFSQKSN LIEHERIHTG EKPYECKECG KSFSQKQNLI EHEKIHTGEK PYACNECGRA FSRMSSVTLH MRSHTGEKPY KCNKCGKAFS QCSVFIIHMR SHTGEKPYVC SECGKAFSQS SSLTVHMRNH TAEKPYECKE CGKAFSRKEN LITHQKIHTG EKPYECSECG KAFIQMSNLI RHQRIHTGEK PYACTVCGKA FSQKSNLTEH EKIHTGEKPY HCNQCGKAFS QRQNLLEHEK IHTGEKPFKC NECGKAFSRI SSLTLHVRSH TGEKPYECNK CGKAFSQCSL LIIHMRSHTG EKPFECNECG KAFSQRASLS IHKRGHTGER HQVY
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