About Proton-coupled amino acid transporter 3
Proton-coupled amino acid transporter 3 (SLC36A3) is a protein
from Homo sapiens identified by UniProt accession
Q495N2, 470 residues long.
MolForge cross-references it against 0 known binders and
2 disease associations.
Target properties
| Protein name | Proton-coupled amino acid transporter 3 |
|---|
| UniProt accession | Q495N2 |
|---|
| Gene | SLC36A3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 470 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (2)
Diseases linked to this target (Open Targets).
- Tay-Sachs disease · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q495N2-F1 | alphafold | PREDICTED | 84.22 | — |
Amino-acid sequence (470 residues)
MSLLGRDYNS ELNSLDNGPQ SPSESSSSIT SENVHPAGEA GLSMMQTLIH LLKCNIGTGL LGLPLAIKNA GLLVGPVSLL AIGVLTVHCM VILLNCAQHL SQRLQKTFVN YGEATMYGLE TCPNTWLRAH AVWGRYTVSF LLVITQLGFC SVYFMFMADN LQQMVEKAHV TSNICQPREI LTLTPILDIR FYMLIILPFL ILLVFIQNLK VLSVFSTLAN ITTLGSMALI FEYIMEGIPY PSNLPLMANW KTFLLFFGTA IFTFEGVGMV LPLKNQMKHP QQFSFVLYLG MSIVIILYIL LGTLGYMKFG SDTQASITLN LPNCWLYQSV KLMYSIGIFF TYALQFHVPA EIIIPFAISQ VSESWALFVD LSVRSALVCL TCVSAILIPR LDLVISLVGS VSSSALALII PALLEIVIFY SEDMSCVTIA KDIMISIVGL LGCIFGTYQA LYELPQPISH SMANSTGVHA
Explore Proton-coupled amino acid transporter 3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets