About Neuritin-like protein
Neuritin-like protein (NRN1L) is a protein
from Homo sapiens identified by UniProt accession
Q496H8, 165 residues long.
MolForge cross-references it against 0 known binders and
35 disease associations.
Target properties
| Protein name | Neuritin-like protein |
|---|
| UniProt accession | Q496H8 |
|---|
| Gene | NRN1L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 165 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (35)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.22
- apolipoprotein A 1 measurement · score 0.19
- HDL cholesterol change measurement · score 0.15
- physical activity · score 0.15
- stem Cell Factor measurement · score 0.14
- hemoglobin measurement · score 0.14
- hematocrit · score 0.13
- total cholesterol measurement · score 0.10
- sleep duration · score 0.09
- triglyceride measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q496H8-F1 | alphafold | PREDICTED | 72.95 | — |
Amino-acid sequence (165 residues)
MMRCCRRRCC CRQPPHALRP LLLLPLVLLP PLAAAAAGPN RCDTIYQGFA ECLIRLGDSM GRGGELETIC RSWNDFHACA SQVLSGCPEE AAAVWESLQQ EARQAPRPNN LHTLCGAPVH VRERGTGSET NQETLRATAP ALPMAPAPPL LAAALALAYL LRPLA
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