About Zinc finger protein 672
Zinc finger protein 672 (ZNF672) is a protein
from Homo sapiens identified by UniProt accession
Q499Z4, 452 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Zinc finger protein 672 |
| UniProt accession | Q499Z4 |
| Gene | ZNF672 |
| Organism | Homo sapiens |
| Length | 452 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.12
- pathological myopia · score 0.07
- hypertension · score 0.04
- monocyte count · score 0.02
- systolic blood pressure · score 0.02
- erythrocyte count · score 0.02
- Adenomyosis · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q499Z4-F1 | alphafold | PREDICTED | 75.79 | — |
Amino-acid sequence (452 residues)
MFATSGAVAA GKPYSCSECG KSFCYSSVLL RHERAHGGDG RFRCLECGER CARAADLRAH RRTHAGQTLY ICSECGQSFR HSGRLDLHLG AHRQRCRTCP CRTCGRRFPH LPALLLHRRR QHLPERPRRC PLCARTFRQS ALLFHQARAH PLGTTSDPAA PPHRCAQCPR AFRSGAGLRS HARIHVSRSP TRPRVSDAHQ CGVCGKCFGK SSTLTRHLQT HSGEKPFKCP ECGKGFLESA TLVRHQRTHT GEKPYACGDC GRCFSESSTL LRHRRSHQGE RPHACATCGK GFGQRSDLVV HQRIHTGEKP FACPECGRRF SDRSDLTKHR RTHTGEKPYR CELCGKRFTC VSNLNVHRRN HAGHKPHKCP ECSKAFSVAS KLALHRKTHL GERPAECAEC GKCFSHSRSL SQHQRAHTRA RTAAAVAIQS AVGTALVFEG PAEQEKPGFS VS
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