About Polypeptide N-acetylgalactosaminyltransferase-like 6
Polypeptide N-acetylgalactosaminyltransferase-like 6 (GALNTL6) is a protein
from Homo sapiens identified by UniProt accession
Q49A17, 601 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | Polypeptide N-acetylgalactosaminyltransferase-like 6 |
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| UniProt accession | Q49A17 |
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| Gene | GALNTL6 |
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| Organism | Homo sapiens |
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| Length | 601 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (32)
Diseases linked to this target (Open Targets).
- delusional disorder · score 0.41
- schizophrenia · score 0.41
- schizotypal personality disorder · score 0.33
- blood protein measurement · score 0.32
- drug use measurement · score 0.31
- smoking behavior · score 0.26
- smoking status measurement · score 0.26
- protein measurement · score 0.25
- self reported educational attainment · score 0.24
- body mass index · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q49A17-F1 | alphafold | PREDICTED | 90.87 | — |
Amino-acid sequence (601 residues)
MKRKQKRFLQ MTLLFTVALI FLPNVGLWSL YKDKHLVKSA EPGEQQTFPL GLGDGQFYSW TDGLRRKDWH DYESIQKEAM RSGKGEHGKP YPLTEEDHDD SAYRENGFNI FVSNNIALER SLPDIRHANC KHKMYLERLP NTSIIIPFHN EGWTSLLRTI HSIINRTPGS LIAEIILVDD FSEREHLKDK LEEYMARFSK VRIVRTKKRE GLIRTRLLGA SMARGEVLTF LDSHCEVNVN WLPPLLNQIA LNHKTIVCPM IDVIDHNHFG YEAQAGDAMR GAFDWEMYYK RIPIPPELQR ADPSDPFESP VMAGGLFAVD RKWFWELGGY DPGLEIWGGE QYEISFKVWM CGGEMFDVPC SRVGHIYRKY VPYKVPSGTS LARNLKRVAE TWMDEFAEYI YQRRPEYRHL STGDISAQKE LRKQLKCKDF KWFMAAVAWD VPKYYPPVEP PPAAWGEIRN VAANLCVDSK HGATGTELRL DICVKDGSER TWSHEQLFTF GWREDIRPGE PLHTRKFCFD AISHNSPVTL YDCHGMKGNQ LWGYRKDRTL FHPVSNSCMD CNPAEKKIFM ARCDPLSETQ QWIFEHINMT VLEKFNHHAN S
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