Zinc finger protein 69 homolog (ZFP69)

About Zinc finger protein 69 homolog

Zinc finger protein 69 homolog (ZFP69) is a protein from Homo sapiens identified by UniProt accession Q49AA0, 526 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	Zinc finger protein 69 homolog
UniProt accession	Q49AA0
Gene	ZFP69
Organism	Homo sapiens
Length	526 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

acute myeloid leukemia · score 0.18
pancreatic adenocarcinoma · score 0.14
lymphocyte count · score 0.09
FTH1-related iron overload · score 0.04
hemochromatosis type 5 · score 0.04
diabetes mellitus · score 0.03
heel bone mineral density · score 0.03
Obesity · score 0.02
type 2 diabetes mellitus · score 0.02
Insulin resistance · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q49AA0-F1	alphafold	PREDICTED	65.27	—

Amino-acid sequence (526 residues)

MPQQLLITLP TEASTWVKLQ HPKKAVEGAP LWEDVTKMFE GEALLSQDAE DVKTQRESLE DEVTPGLPTA ESQELLTFKD ISIDFTQEEW GQLAPAHQNL YREVMLENYS NLVSVGYQLS KPSVISQLEK GEEPWMAEKE GPGDPSSDLK SKIETIESTA KSTISQERLY HGIMMESFMR DDIIYSTLRK VSTYDDVLER HQETCMRDVR QAILTHKKRV QETNKFGENI IVHSNVIIEQ RHHKYDTPTK RNTYKLDLIN HPTSYIRTKT YECNICEKIF KQPIHLTEHM RIHTGEKPFR CKECGRAFSQ SASLSTHQRI HTGEKPFECE ECGKAFRHRS SLNQHHRTHT GEKPYVCDKC QKAFSQNISL VQHLRTHSGE KPFTCNECGK TFRQIRHLSE HIRIHTGEKP YACTACCKTF SHRAYLTHHQ RIHTGERPYK CKECGKAFRQ RIHLSNHKTV HTGVKAYECN RCGKAYRHDS SFKKHQRHHT GEKPYECNEC GKAFSYNSSL SRHHEIHRRN AFRNKV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards