About Zinc finger BED domain-containing protein 5
Zinc finger BED domain-containing protein 5 (ZBED5) is a protein
from Homo sapiens identified by UniProt accession
Q49AG3, 693 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | Zinc finger BED domain-containing protein 5 |
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| UniProt accession | Q49AG3 |
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| Gene | ZBED5 |
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| Organism | Homo sapiens |
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| Length | 693 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (20)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.26
- waist-hip ratio · score 0.25
- heel bone mineral density · score 0.22
- BMI-adjusted waist circumference · score 0.19
- lung adenocarcinoma · score 0.08
- dimethylamine measurement · score 0.04
- gut microbiome measurement · score 0.04
- cerebrospinal fluid biomarker measurement · score 0.03
- skin pigmentation measurement · score 0.03
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q49AG3-F1 | alphafold | PREDICTED | 81.37 | — |
Amino-acid sequence (693 residues)
MIAPLLCILS YNFNTFAILN VYSKLTMFCT TNSLPMDLLL KQGSLKQEVE SFCYQIVSES NDQKVGILQS EDKQLQPSVS KKSEGELSRV KFISNSNKIT FSKKPKRRKY DESYLSFGFT YFGNRDAPHA QCVLCKKILS NSSLAPSKLR RHLETKHAAY KDKDISFFKQ HLDSPENNKP PTPKIVNTDN ESATEASYNV SYHIALSGEA HTIGELLIKP CAKDVVMRMF DEQYSKKIDA VQLSNSTVAR RIKDLAADIE EELVCRLKIC DGFSLQLDES ADVSGLAVLL VFVRYRFNKS IEEDLLLCES LQSNATGEEI FNCINSFMQK HEIEWEKCVD VCSDASRAVD GKIAEAVTLI KYVAPESTSS HCLLYRHALA VKIMPTSLKN VLDQAVQIIN YIKARPHQSR LLKILCEEMG AQHTALLLNT EVRWLSRGKV LVRLFELRRE LLVFMDSAFR LSDCLTNSSW LLRLAYLADI FTKLNEVNLS MQGKNVTVFT VFDKMSSLLR KLEFWASSVE EENFDCFPTL SDFLTEINST VDKDICSAIV QHLRGLRATL LKYFPVTNDN NAWVRNPFTV TVKPASLVAR DYESLIDLTS DSQVKQNFSE LSLNDFWSSL IQEYPSIARR AVRVLLPFAT MHLCETGFSY YAATKTKYRK RLDAAPHMRI RLSNITPNIK RICDKKTQKH CSH
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