Cytochrome c oxidase assembly protein COX19 (COX19)

About Cytochrome c oxidase assembly protein COX19

Cytochrome c oxidase assembly protein COX19 (COX19) is a protein from Homo sapiens identified by UniProt accession Q49B96, 90 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.

Target properties

Protein name	Cytochrome c oxidase assembly protein COX19
UniProt accession	Q49B96
Gene	COX19
Organism	Homo sapiens
Length	90 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (50)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.49
platelet count · score 0.22
triglyceride measurement · score 0.21
alkaline phosphatase measurement · score 0.21
lymphocyte percentage of leukocytes · score 0.21
C-reactive protein measurement · score 0.20
lymphocyte count · score 0.20
serum gamma-glutamyl transferase measurement · score 0.20
lung adenocarcinoma · score 0.18
squamous cell lung carcinoma · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q49B96-F1	alphafold	PREDICTED	80.52	—

Amino-acid sequence (90 residues)

MSTAMNFGTK SFQPRPPDKG SFPLDHLGEC KSFKEKFMKC LHNNNFENAL CRKESKEYLE CRMERKLMLQ EPLEKLGFGD LTSGKSEAKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards