About Microtubule-associated protein 9
Microtubule-associated protein 9 (MAP9) is a protein
from Homo sapiens identified by UniProt accession
Q49MG5, 647 residues long.
MolForge cross-references it against 0 known binders and
49 disease associations.
Target properties
| Protein name | Microtubule-associated protein 9 |
|---|
| UniProt accession | Q49MG5 |
|---|
| Gene | MAP9 |
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| Organism | Homo sapiens |
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| Length | 647 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (49)
Diseases linked to this target (Open Targets).
- pulse pressure measurement · score 0.44
- systolic blood pressure · score 0.36
- temporal horn of lateral ventricle volume measurement · score 0.32
- hypertension · score 0.32
- coronary artery disease · score 0.31
- cardiovascular disease · score 0.31
- Agents acting on the renin-angiotensin system use measurement · score 0.26
- Diuretic use measurement · score 0.24
- Calcium channel blocker use measurement · score 0.24
- Vasodilators used in cardiac diseases use measurement · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q49MG5-F1 | alphafold | PREDICTED | 61.24 | — |
Amino-acid sequence (647 residues)
MSDEVFSTTL AYTKSPKVTK RTTFQDELIR AITARSARQR SSEYSDDFDS DEIVSLGDFS DTSADENSVN KKMNDFHISD DEEKNPSKLL FLKTNKSNGN ITKDEPVCAI KNEEEMAPDG CEDIVVKSFS ESQNKDEEFE KDKIKMKPKP RILSIKSTSS AENNSLDTDD HFKPSPRPRS MLKKKSHMEE KDGLEDKETA LSEELELHSA PSSLPTPNGI QLEAEKKAFS ENLDPEDSCL TSLASSSLKQ ILGDSFSPGS EGNASGKDPN EEITENHNSL KSDENKENSF SADHVTTAVE KSKESQVTAD DLEEEKAKAE LIMDDDRTVD PLLSKSQSIL ISTSATASSK KTIEDRNIKN KKSTNNRASS ASARLMTSEF LKKSSSKRRT PSTTTSSHYL GTLKVLDQKP SQKQSIEPDR ADNIRAAVYQ EWLEKKNVYL HEMHRIKRIE SENLRIQNEQ KKAAKREEAL ASFEAWKAMK EKEAKKIAAK KRLEEKNKKK TEEENAARKG EALQAFEKWK EKKMEYLKEK NRKEREYERA KKQKEEETVA EKKKDNLTAV EKWNEKKEAF FKQKEKEKIN EKRKEELKRA EKKDKDKQAI NEYEKWLENK EKQERIERKQ KKRHSFLESE ALPPWSPPSR TVFAKVF
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