Cortexin-3 (CTXN3)

About Cortexin-3

Cortexin-3 (CTXN3) is a protein from Homo sapiens identified by UniProt accession Q4LDR2, 81 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein name	Cortexin-3
UniProt accession	Q4LDR2
Gene	CTXN3
Organism	Homo sapiens
Length	81 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (29)

Diseases linked to this target (Open Targets).

Red cell distribution width · score 0.33
FEV/FVC ratio · score 0.29
fungal infectious disease · score 0.16
schizophrenia · score 0.08
clear cell renal carcinoma · score 0.06
central nervous system cancer · score 0.06
hemoglobin measurement · score 0.04
erythrocyte count · score 0.04
Cluster headache · score 0.04
hematocrit · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q4LDR2-F1	alphafold	PREDICTED	70.20	—

Amino-acid sequence (81 residues)

MDGGQPIPSS LVPLGNESAD SSMSLEQKMT FVFVILLFIF LGILIVRCFR ILLDPYRSMP TSTWADGLEG LEKGQFDHAL A

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards