G antigen 2E (GAGE2E)

About G antigen 2E

G antigen 2E (GAGE2E) is a protein from Homo sapiens identified by UniProt accession Q4V326, 110 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.

Target properties

Protein name	G antigen 2E
UniProt accession	Q4V326
Gene	GAGE2E
Organism	Homo sapiens
Length	110 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (3)

Diseases linked to this target (Open Targets).

genetic disorder · score 0.12
cancer · score 0.01
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q4V326-F1	alphafold	PREDICTED	63.38	—

Amino-acid sequence (110 residues)

MSWRGRSTYY WPRPRRYVQP PEMIGPMRPE QFSDEVEPAT PEEGEPATQR QDPAAAQEGE DEGASAGQGP KPEAHSQEQG HPQTGCECED GPDGQEMDPP NPEEVKTPEE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards