About B-cell CLL/lymphoma 7 protein family member A
B-cell CLL/lymphoma 7 protein family member A (BCL7A) is a protein
from Homo sapiens identified by UniProt accession
Q4VC05, 210 residues long.
MolForge cross-references it against 0 known binders and
156 disease associations.
Target properties
| Protein name | B-cell CLL/lymphoma 7 protein family member A |
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| UniProt accession | Q4VC05 |
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| Gene | BCL7A |
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| Organism | Homo sapiens |
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| Length | 210 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (156)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- multiple myeloma · score 0.39
- Burkitts lymphoma · score 0.37
- diastolic blood pressure · score 0.35
- lymphoma · score 0.27
- urinary metabolite measurement · score 0.26
- diffuse large B-cell lymphoma · score 0.21
- acute myeloid leukemia · score 0.21
- mean corpuscular volume · score 0.20
- red blood cell density measurement · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q4VC05-F1 | alphafold | PREDICTED | 62.42 | — |
Amino-acid sequence (210 residues)
MSGRSVRAET RSRAKDDIKR VMAAIEKVRK WEKKWVTVGD TSLRIYKWVP VTEPKVDDKN KNKKKGKDEK CGSEVTTPEN SSSPGMMDMH DDNSNQSSIA DASPIKQENS SNSSPAPEPN SAVPSDGTEA KVDEAQADGK EHPGAEDASD EQNSQSSMEH SMNSSEKVDR QPSGDSGLAA ETSAISQDLE GVPPSKKMKL EASQQNSEEM
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