About Coiled-coil domain-containing protein 38
Coiled-coil domain-containing protein 38 (CCDC38) is a protein
from Homo sapiens identified by UniProt accession
Q502W7, 563 residues long.
MolForge cross-references it against 0 known binders and
143 disease associations.
Target properties
| Protein name | Coiled-coil domain-containing protein 38 |
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| UniProt accession | Q502W7 |
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| Gene | CCDC38 |
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| Organism | Homo sapiens |
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| Length | 563 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (143)
Diseases linked to this target (Open Targets).
- serum metabolite measurement · score 0.36
- protein measurement · score 0.29
- blood metabolite measurement · score 0.29
- amino acid measurement · score 0.29
- PHF-tau measurement · score 0.28
- hemoglobin measurement · score 0.22
- hematocrit · score 0.15
- refractive error · score 0.13
- Abnormality of refraction · score 0.12
- FEV/FVC ratio · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q502W7-F1 | alphafold | PREDICTED | 72.98 | — |
Amino-acid sequence (563 residues)
MSSNLLPTLN SGGKVKDGST KEDRPYKIFF RDLFLVKENE MAAKETEKFM NRNMKVYQKT TFSSRMKSHS YLSQLAFYPK RSGRSFEKFG PGPAPIPRLI EGSDTKRTVH EFINDQRDRF LLEYALSTKR NTIKKFEKDI AMRERQLKKA EKKLQDDALA FEEFLRENDQ RSVDALKMAA QETINKLQMT AELKKASMEV QAVKSEIAKT EFLLREYMKY GFFLLQMSPK HWQIQQALKR AQASKSKANI ILPKILAKLS LHSSNKEGIL EESGRTAVLS EDASQGRDSQ GKPSRSLTRT PEKKKSNLAE SFGSEDSLEF LLDDEMDVDL EPALYFKEPE ELLQVLRELE EQNLTLFQYS QDVDENLEEV NKREKVIQDK TNSNIEFLLE QEKMLKANCV REEEKAAELQ LKSKLFSFGE FNSDAQEILI DSLSKKITQV YKVCIGDAED DGLNPIQKLV KVESRLVELC DLIESIPKEN VEAIERMKQK EWRQKFRDEK MKEKQRHQQE RLKAALEKAV AQPKKKLGRR LVFHSKPPSG NKQQLPLVNE TKTKSQEEEY FFT
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