About Zinc transporter ZIP12
Zinc transporter ZIP12 (SLC39A12) is a protein
from Homo sapiens identified by UniProt accession
Q504Y0, 691 residues long.
MolForge cross-references it against 0 known binders and
59 disease associations.
Target properties
| Protein name | Zinc transporter ZIP12 |
|---|
| UniProt accession | Q504Y0 |
|---|
| Gene | SLC39A12 |
|---|
| Organism | Homo sapiens |
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| Length | 691 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (59)
Diseases linked to this target (Open Targets).
- aspartate aminotransferase measurement · score 0.48
- neutrophil count · score 0.47
- leukocyte count · score 0.45
- blood protein measurement · score 0.44
- myeloid white cell count · score 0.41
- mathematical ability · score 0.41
- systolic blood pressure · score 0.39
- synophrys measurement · score 0.30
- monocyte count · score 0.30
- serum albumin measurement · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q504Y0-F1 | alphafold | PREDICTED | 69.38 | — |
Amino-acid sequence (691 residues)
MCFRTKLSVS WVPLFLLLSR VFSTETDKPS AQDSRSRGSS GQPADLLQVL SAGDHPPHNH SRSLIKTLLE KTGCPRRRNG MQGDCNLCFE PDALLLIAGG NFEDQLREEV VQRVSLLLLY YIIHQEEICS SKLNMSNKEY KFYLHSLLSL RQDEDSSFLS QNETEDILAF TRQYFDTSQS QCMETKTLQK KSGIVSSEGA NESTLPQLAA MIITLSLQGV CLGQGNLPSP DYFTEYIFSS LNRTNTLRLS ELDQLLNTLW TRSTCIKNEK IHQFQRKQNN IITHDQDYSN FSSSMEKESE DGPVSWDQTC FSARQLVEIF LQKGLSLISK EDFKQMSPGI IQQLLSCSCH LPKDQQAKLP PTTLEKYGYS TVAVTLLTLG SMLGTALVLF HSCEENYRLI LQLFVGLAVG TLSGDALLHL IPQVLGLHKQ EAPEFGHFHE SKGHIWKLMG LIGGIHGFFL IEKCFILLVS PNDKQGLSLV NGHVGHSHHL ALNSELSDQA GRGKSASTIQ LKSPEDSQAA EMPIGSMTAS NRKCKAISLL AIMILVGDSL HNFADGLAIG AAFSSSSESG VTTTIAILCH EIPHEMGDFA VLLSSGLSMK TAILMNFISS LTAFMGLYIG LSVSADPCVQ DWIFTVTAGM FLYLSLVEML PEMTHVQTQR PWMMFLLQNF GLILGWLSLL LLAIYEQNIK I
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