Zinc finger CW-type PWWP domain protein 2 (ZCWPW2)

About Zinc finger CW-type PWWP domain protein 2

Zinc finger CW-type PWWP domain protein 2 (ZCWPW2) is a protein from Homo sapiens identified by UniProt accession Q504Y3, 356 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein name	Zinc finger CW-type PWWP domain protein 2
UniProt accession	Q504Y3
Gene	ZCWPW2
Organism	Homo sapiens
Length	356 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (19)

Diseases linked to this target (Open Targets).

lymphocyte count · score 0.36
neutrophil percentage of leukocytes · score 0.31
Red cell distribution width · score 0.30
lymphocyte percentage of leukocytes · score 0.28
platelet-to-lymphocyte ratio · score 0.25
multiple sclerosis · score 0.15
systemic lupus erythematosus · score 0.12
Epstein Barr virus nuclear antigen 1 IgG measurement · score 0.10
mathematical ability · score 0.07
periodontal measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q504Y3-F1	alphafold	PREDICTED	72.45	—

Amino-acid sequence (356 residues)

MDKEKLDVKI EYCNYAMDSS VENMYVNKVW VQCENENCLK WRLLSSEDSA KVDHDEPWYC FMNTDSRYNN CSISEEDFPE ESQLHQCGFK IVYSQLPLGS LVLVKLQNWP SWPGILCPDR FKGKYVTYDP DGNVEEYHIE FLGDPHSRSW IKATFVGHYS ITLKPEKCKN KKKWYKSALQ EACLLYGYSH EQRLEMCCLS KLQDKSETHD KVAALVKKRK QTSKNNIEKK KPKFRKRKRK AILKCSFENV YSDDALSKEN RVVCETEVLL KELEQMLQQA LQPTATPDES EEGHGEEINM GEKLSKCSPE APAGSLFENH YEEDYLVIDG IKLKAGECIE DITNKFKEID ALMSEF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards