About Leucine-rich repeat-containing protein 24
Leucine-rich repeat-containing protein 24 (LRRC24) is a protein
from Homo sapiens identified by UniProt accession
Q50LG9, 513 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Leucine-rich repeat-containing protein 24 |
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| UniProt accession | Q50LG9 |
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| Gene | LRRC24 |
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| Organism | Homo sapiens |
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| Length | 513 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (13)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.26
- self reported educational attainment · score 0.16
- intelligence · score 0.16
- cognitive function measurement · score 0.14
- type 2 diabetes mellitus · score 0.11
- serum alanine aminotransferase measurement · score 0.10
- mean corpuscular hemoglobin concentration · score 0.07
- smoking status measurement · score 0.06
- blood metabolite measurement · score 0.04
- testosterone measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q50LG9-F1 | alphafold | PREDICTED | 76.97 | — |
Amino-acid sequence (513 residues)
MALRAPALLP LLLLLLPLRA AGCPAACRCY SATVECGALR LRVVPLGIPP GTQTLFLQDN NIARLEPGAL APLAALRRLY LHNNSLRALE AGAFRAQPRL LELALTSNRL RGLRSGAFVG LAQLRVLYLA GNQLARLLDF TFLHLPRLQE LHLQENSIEL LEDQALAGLS SLALLDLSRN QLGTISREAL QPLASLQVLR LTENPWRCDC ALHWLGAWIK EGGQRLLTSR DRKIMCAEPP RLALQSLLDV SHSSLICIPP SVHVQPLELT ANLGEDLRVA CQASGYPQPL VTWRKVPQPR EGRPRAQAQL EGGLLGLGGH SASDTGSGML FLSNITLAHA GKYECEASNA GGAARVPFRL LVNASRQQPQ QPAQPPPPAA RPAGSEPRPE AGSMAFRALG VATQTAIAAA IALLALTALL LVAMICRRRR RRKKARGPPG EGALFVNDYL DGPCTFAQLE ELRDERGHEM FVINRSKPLF AEGPAEAPAD CGPEQGAGPG LRVPPPVAYE IHC
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