About Raftlin-2
Raftlin-2 (RFTN2) is a protein
from Homo sapiens identified by UniProt accession
Q52LD8, 501 residues long.
MolForge cross-references it against 0 known binders and
73 disease associations.
Target properties
| Protein name | Raftlin-2 |
|---|
| UniProt accession | Q52LD8 |
|---|
| Gene | RFTN2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 501 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q52LD8-F1 | alphafold | PREDICTED | 68.27 | — |
Amino-acid sequence (501 residues)
MGCGLRKLED PDDSSPGKIF STLKRPQVET KTEFAYEYVL LDFTLQASSN PEVIKINSIL DIVTKVENYY LKGYIVGAIH PVIQPVGQRK HLPASYLYRV VLLRLKLSPK NSAAPSGQRR PRLVIEECPL TSEAQTNDAA KELIEKINVA AKRGMKFVGF ISQHYSPSKF CNGTNHDGDI ESMLHVRHGS DENCRSWNEG TLSGQSSESG IEEELHHESG QYQMEQNGSP TSSKSRKGEA SDNKLYTVFN AFDDDSTSWA YQEGILSMKV TRKGSVISTL DADWLELTTF YYKQGLSLID SFVFWETSKG EHLPKSLEGF FIYEEEGSGV PGSSRKGNDA IVVEQWTVIE GCEIKTDYGP LLHTLAEFGW LLTSVLPTPV LRHDSEGNLA TKQIVFLQRP VMWNSAAQTP DKKASRHIKG EDKNKATSRS IGLDTTSSQP AESRHLPEEC RLSPSRECWT KEGRLAQHNS FSGFSSSDNV LRELDDGQFD QEDGVTQVTC M
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