Keratin-associated protein 13-2 (KRTAP13-2)

About Keratin-associated protein 13-2

Keratin-associated protein 13-2 (KRTAP13-2) is a protein from Homo sapiens identified by UniProt accession Q52LG2, 175 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

Target properties

Protein name	Keratin-associated protein 13-2
UniProt accession	Q52LG2
Gene	KRTAP13-2
Organism	Homo sapiens
Length	175 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (10)

Diseases linked to this target (Open Targets).

head and neck squamous cell carcinoma · score 0.18
clear cell renal carcinoma · score 0.18
colorectal cancer · score 0.02
Crohn's disease · score 0.01
ulcerative colitis · score 0.01
COVID-19 · score 0.01
colorectal adenocarcinoma · score 0.00
neoplasm · score 0.00
melanoma · score 0.00
cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q52LG2-F1	alphafold	PREDICTED	46.56	—

Amino-acid sequence (175 residues)

MSYNCCSGNF SSRSCGDYLR YPASSRGFSY PSNLVYSTDL CSPSTCQLGS SLYRGCQEIC WEPTSCQTSY VESSPCQTSC YRPRTSLLCS PCKTTYSGSL GFGSSSCRSL GYGSRSCYSV GCGSSGVRSL GYGSCGFPSL GYGSGFCRPT YLASRSCQSP CYRPAYGSTF CRSTC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards