About Zinc finger protein 585B
Zinc finger protein 585B (ZNF585B) is a protein
from Homo sapiens identified by UniProt accession
Q52M93, 769 residues long.
MolForge cross-references it against 0 known binders and
27 disease associations.
Target properties
| Protein name | Zinc finger protein 585B |
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| UniProt accession | Q52M93 |
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| Gene | ZNF585B |
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| Organism | Homo sapiens |
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| Length | 769 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (27)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.24
- insomnia · score 0.15
- eosinophil percentage of leukocytes · score 0.09
- insomnia measurement · score 0.07
- body height · score 0.07
- glomerular filtration rate · score 0.06
- gait measurement · score 0.06
- forced expiratory volume · score 0.05
- BMI-adjusted waist circumference · score 0.05
- grip strength measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q52M93-F1 | alphafold | PREDICTED | 75.24 | — |
Amino-acid sequence (769 residues)
MPASWTSPQK SSALAPEDHG SSYEGSVSFR DVAIDFSREE WRHLDLSQRN LYRDVMLETY SHLLSVGYQV PKPEVVMLEQ GKEPWALQGE RPRHSCPGEK LWDHNQHRKI IGYKPASSQD QKIYSGEKSY ECAEFGKSFT WKSQFKVHLK VPTGEKLYVC IECGRAFVQK PEFITHQKTH MREKPYKCNE CGKSFFQVSS LFRHHRIHTG EKLYECSECG KGFPYNSDLS IHEKIHTGER HHECTDCGKA FTQKSTLKIH QKIHTGERSY ICIECGQAFI QKTQLIAHRR IHSGEKPYEC NNCGKSFISK SQLQVHQRVH TRVKPYICTE YGKVFSNNSN LITHEKIQSR EKSSICTECG KAFTYRSELI IHQRIHTGEK PYECSDCGRA FTQKSALTVH QRIHTGEKSY ICMKCGLAFI RKAHLITHQI IHTGEKPYKC GHCGKLFTSK SQLHVHKRIH TGEKPYVCNK CGKAFTNRSN LITHQKTHTG EKSYICSKCG KAFTQRSDLI THQRIHTGEK PYECNTCGKA FTQKSNLNIH QKIHTGERQY ECHECGKAFN QKSILIVHQK IHTGEKPYVC TECGRAFIRK SNFITHQRIH TGEKPYECSD CGKSFTSKSQ LLVHQPVHTG EKPYVCAECG KAFSGRSNLS KHQKTHTGEK PYICSECGKT FRQKSELITH HRIHTGEKPY ECSDCGKSFT KKSQLQVHQR IHTGEKPYVC AECGKAFSNR SNLNKHQTTH TGDKPYKCGI CGKGFVQKSV FSVHQSSHA
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