About Quinone oxidoreductase PIG3
Quinone oxidoreductase PIG3 (TP53I3) is a protein
from Homo sapiens identified by UniProt accession
Q53FA7, 332 residues long.
MolForge cross-references it against 0 known binders and
58 disease associations.
Target properties
| Protein name | Quinone oxidoreductase PIG3 |
|---|
| UniProt accession | Q53FA7 |
|---|
| Gene | TP53I3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 332 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (58)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.25
- lung adenocarcinoma · score 0.24
- esophageal cancer · score 0.23
- urinary bladder cancer · score 0.23
- cutaneous melanoma · score 0.13
- lifestyle measurement · score 0.07
- metabolite measurement · score 0.05
- sum of basophil and neutrophil counts · score 0.05
- platelet component distribution width · score 0.04
- neutrophil count · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q53FA7-F1 | alphafold | PREDICTED | 97.04 | — |
Amino-acid sequence (332 residues)
MLAVHFDKPG GPENLYVKEV AKPSPGEGEV LLKVAASALN RADLMQRQGQ YDPPPGASNI LGLEASGHVA ELGPGCQGHW KIGDTAMALL PGGGQAQYVT VPEGLLMPIP EGLTLTQAAA IPEAWLTAFQ LLHLVGNVQA GDYVLIHAGL SGVGTAAIQL TRMAGAIPLV TAGSQKKLQM AEKLGAAAGF NYKKEDFSEA TLKFTKGAGV NLILDCIGGS YWEKNVNCLA LDGRWVLYGL MGGGDINGPL FSKLLFKRGS LITSLLRSRD NKYKQMLVNA FTEQILPHFS TEGPQRLLPV LDRIYPVTEI QEAHKYMEAN KNIGKIVLEL PQ
Explore Quinone oxidoreductase PIG3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets