Uncharacterized protein C4orf17 (C4orf17)

About Uncharacterized protein C4orf17

Uncharacterized protein C4orf17 (C4orf17) is a protein from Homo sapiens identified by UniProt accession Q53FE4, 359 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	Uncharacterized protein C4orf17
UniProt accession	Q53FE4
Gene	C4orf17
Organism	Homo sapiens
Length	359 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

alcohol consumption measurement · score 0.40
viral load · score 0.30
alcohol use disorder measurement · score 0.25
apolipoprotein A 1 measurement · score 0.19
body height · score 0.17
triglyceride measurement · score 0.07
serum alanine aminotransferase measurement · score 0.05
alcohol dependence measurement · score 0.04
platelet component distribution width · score 0.04
aspartate aminotransferase measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q53FE4-F1	alphafold	PREDICTED	56.18	—

Amino-acid sequence (359 residues)

MNLNPPTSAL QIEGKGSHIM ARNVSCFLVR HTPHPRRVCH IKGLNNIPIC TVNDDENAFG TLWGVGQSNY LEKNRIPFAN CSYPSSTAVQ ESPVRGMSPA PNGAKVPPRP HSEPSRKIKE CFKTSSENPL VIKKEEIKAK RPPSPPKACS TPGSCSSGMT STKNDVKANT ICIPNYLDQE IKILAKLCSI LHTDSLAEVL QWLLHATSKE KEWVSALIHS ELAEINLLTH HRRNTSMEPA AETGKPPTVK SPPTVKLPPN FTAKSKVLTR DTEGDQPTRV SSQGSEENKE VPKEAEHKPP LLIRRNNMKI PVAEYFSKPN SPPRPNTQES GSAKPVSARS IQEYNLCPQR ACYPSTHRR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards