About Protein Hikeshi
Protein Hikeshi (HIKESHI) is a protein
from Homo sapiens identified by UniProt accession
Q53FT3, 197 residues long.
MolForge cross-references it against 0 known binders and
46 disease associations.
Target properties
| Protein name | Protein Hikeshi |
|---|
| UniProt accession | Q53FT3 |
|---|
| Gene | HIKESHI |
|---|
| Organism | Homo sapiens |
|---|
| Length | 197 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (46)
Diseases linked to this target (Open Targets).
- hypomyelinating leukodystrophy 13 · score 0.66
- Hypomyelinating leukodystrophy with or without oligondontia and/or hypogonadism · score 0.37
- genetic disorder · score 0.32
- IGF-1 measurement · score 0.31
- cystatin C measurement · score 0.29
- insulin like growth factor measurement · score 0.26
- mean platelet volume · score 0.15
- Alzheimer disease · score 0.07
- family history of Alzheimer’s disease · score 0.07
- mean reticulocyte volume · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q53FT3-F1 | alphafold | PREDICTED | 88.85 | — |
Amino-acid sequence (197 residues)
MFGCLVAGRL VQTAAQQVAE DKFVFDLPDY ESINHVVVFM LGTIPFPEGM GGSVYFSYPD SNGMPVWQLL GFVTNGKPSA IFKISGLKSG EGSQHPFGAM NIVRTPSVAQ IGISVELLDS MAQQTPVGNA AVSSVDSFTQ FTQKMLDNFY NFASSFAVSQ AQMTPSPSEM FIPANVVLKW YENFQRRLAQ NPLFWKT
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