Zinc finger protein 394 (ZNF394)

About Zinc finger protein 394

Zinc finger protein 394 (ZNF394) is a protein from Homo sapiens identified by UniProt accession Q53GI3, 561 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Zinc finger protein 394
UniProt accession	Q53GI3
Gene	ZNF394
Organism	Homo sapiens
Length	561 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

acute myeloid leukemia · score 0.18
body fat percentage · score 0.15
body mass index · score 0.10
mean corpuscular volume · score 0.10
lean body mass · score 0.09
smoking status measurement · score 0.09
reticulocyte count · score 0.09
fat body mass · score 0.09
mean platelet volume · score 0.09
age at first sexual intercourse measurement · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q53GI3-F1	alphafold	PREDICTED	61.17	—

Amino-acid sequence (561 residues)

MNSSLTAQRR GSDAELGPWV MAARSKDAAP SQRDGLLPVK VEEDSPGSWE PNYPAASPDP ETSRLHFRQL RYQEVAGPEE ALSRLRELCR RWLRPELLSK EQILELLVLE QFLTILPEEL QAWVREHCPE SGEEAVAVVR ALQRALDGTS SQGMVTFEDT AVSLTWEEWE RLDPARRDFC RESAQKDSGS TVPPSLESRV ENKELIPMQQ ILEEAEPQGQ LQEAFQGKRP LFSKCGSTHE DRVEKQSGDP LPLKLENSPE AEGLNSISDV NKNGSIEGED SKNNELQNSA RCSNLVLCQH IPKAERPTDS EEHGNKCKQS FHMVTWHVLK PHKSDSGDSF HHSSLFETQR QLHEERPYKC GNCGKSFKQR SDLFRHQRIH TGEKPYGCQE CGKSFSQSAA LTKHQRTHTG EKPYTCLKCG ERFRQNSHLN RHQSTHSRDK HFKCEECGET CHISNLFRHQ RLHKGERPYK CEECEKSFKQ RSDLFKHHRI HTGEKPYGCS VCGKRFNQSA TLIKHQRIHT GEKPYKCLEC GERFRQSTHL IRHQRIHQNK VLSAGRGGSR L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards