Putative ANKRD40 C-terminal-like protein (ANKRD40CL)

About Putative ANKRD40 C-terminal-like protein

Putative ANKRD40 C-terminal-like protein (ANKRD40CL) is a protein from Homo sapiens identified by UniProt accession Q53H64, 114 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Putative ANKRD40 C-terminal-like protein
UniProt accession	Q53H64
Gene	ANKRD40CL
Organism	Homo sapiens
Length	114 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

alkaline phosphatase measurement · score 0.22
Barrett's esophagus · score 0.07
esophageal adenocarcinoma · score 0.05
neoplasm · score 0.04
heel bone mineral density · score 0.03
lung adenocarcinoma · score 0.03
breast cancer · score 0.01
pancreatic ductal adenocarcinoma · score 0.01
ulcerative colitis · score 0.01
colorectal cancer · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q53H64-F1	alphafold	PREDICTED	77.78	—

Amino-acid sequence (114 residues)

MAEPEQDIGE KPAVRIQNPK ENDFIEIELK RQELSYQNLL NVSCCELGIK PERVEKIRKL PNTLLRKDKD IRRLRDFQEV ELILMKNGSS RLTEYVPSLT ERPCYDSKAA KMTY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards