About Endoribonuclease LACTB2
Endoribonuclease LACTB2 (LACTB2) is a protein
from Homo sapiens identified by UniProt accession
Q53H82, 288 residues long.
MolForge cross-references it against 0 known binders and
50 disease associations.
Target properties
| Protein name | Endoribonuclease LACTB2 |
|---|
| UniProt accession | Q53H82 |
|---|
| Gene | LACTB2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 288 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (50)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.23
- heel bone mineral density · score 0.23
- blood phosphate measurement · score 0.21
- cortical surface area measurement · score 0.20
- BMI-adjusted waist circumference · score 0.16
- hemorrhoid · score 0.16
- urate measurement · score 0.16
- Snoring · score 0.15
- vital capacity · score 0.14
- bone quantitative ultrasound measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q53H82-F1 | alphafold | PREDICTED | 95.76 | — |
Amino-acid sequence (288 residues)
MAAVLQRVER LSNRVVRVLG CNPGPMTLQG TNTYLVGTGP RRILIDTGEP AIPEYISCLK QALTEFNTAI QEIVVTHWHR DHSGGIGDIC KSINNDTTYC IKKLPRNPQR EEIIGNGEQQ YVYLKDGDVI KTEGATLRVL YTPGHTDDHM ALLLEEENAI FSGDCILGEG TTVFEDLYDY MNSLKELLKI KADIIYPGHG PVIHNAEAKI QQYISHRNIR EQQILTLFRE NFEKSFTVME LVKIIYKNTP ENLHEMAKHN LLLHLKKLEK EGKIFSNTDP DKKWKAHL
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