Coiled-coil domain-containing protein 92 (CCDC92)

About Coiled-coil domain-containing protein 92

Coiled-coil domain-containing protein 92 (CCDC92) is a protein from Homo sapiens identified by UniProt accession Q53HC0, 331 residues long. MolForge cross-references it against 0 known binders and 116 disease associations.

Target properties

Protein name	Coiled-coil domain-containing protein 92
UniProt accession	Q53HC0
Gene	CCDC92
Organism	Homo sapiens
Length	331 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (116)

Diseases linked to this target (Open Targets).

BMI-adjusted waist-hip ratio · score 0.45
body fat percentage · score 0.45
high density lipoprotein cholesterol measurement · score 0.44
neurodegenerative disease · score 0.44
triglyceride measurement · score 0.42
urate measurement · score 0.41
leukocyte count · score 0.41
sex hormone-binding globulin measurement · score 0.40
BMI-adjusted waist circumference · score 0.39
lymphocyte count · score 0.38

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q53HC0-F1	alphafold	PREDICTED	73.30	—

Amino-acid sequence (331 residues)

MTSPHFSSYD EGPLDVSMAA TNLENQLHSA QKNLLFLQRE HASTLKGLHS EIRRLQQHCT DLTYELTVKS SEQTGDGTSK SSELKKRCEE LEAQLKVKEN ENAELLKELE QKNAMITVLE NTIKEREKKY LEELKAKSHK LTLLSSELEQ RASTIAYLTS QLHAAKKKLM SSSGTSDASP SGSPVLASYK PAPPKDKLPE TPRRRMKKSL SAPLHPEFEE VYRFGAESRK LLLREPVDAM PDPTPFLLAR ESAEVHLIKE RPLVIPPIAS DRSGEQHSPA REKPHKAHVG VAHRIHHATP PQAQPEVKTL AVDQVNGGKV VRKHSGTDRT V

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards