Fibulin-7 (FBLN7)

About Fibulin-7

Fibulin-7 (FBLN7) is a protein from Homo sapiens identified by UniProt accession Q53RD9, 439 residues long. MolForge cross-references it against 0 known binders and 89 disease associations.

Target properties

Protein name	Fibulin-7
UniProt accession	Q53RD9
Gene	FBLN7
Organism	Homo sapiens
Length	439 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (89)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.31
Varicose veins · score 0.28
myeloid white cell count · score 0.27
brain measurement · score 0.27
cortical thickness · score 0.27
blood protein measurement · score 0.26
high density lipoprotein cholesterol measurement · score 0.23
neutrophil count · score 0.20
systolic blood pressure · score 0.13
sitting height measurement · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q53RD9-F1	alphafold	PREDICTED	82.31	—

Amino-acid sequence (439 residues)

MVPSSPRALF LLLLILACPE PRASQNCLSK QQLLSAIRQL QQLLKGQETR FAEGIRHMKS RLAALQNSVG RVGPDALPVS CPALNTPADG RKFGSKYLVD HEVHFTCNPG FRLVGPSSVV CLPNGTWTGE QPHCRGISEC SSQPCQNGGT CVEGVNQYRC ICPPGRTGNR CQHQAQTAAP EGSVAGDSAF SRAPRCAQVE RAQHCSCEAG FHLSGAAGDS VCQDVNECEL YGQEGRPRLC MHACVNTPGS YRCTCPGGYR TLADGKSCED VDECVGLQPV CPQGTTCINT GGSFQCVSPE CPEGSGNVSY VKTSPFQCER NPCPMDSRPC RHLPKTISFH YLSLPSNLKT PITLFRMATA SAPGRAGPNS LRFGIVGGNS RGHFVMQRSD RQTGDLILVQ NLEGPQTLEV DVDMSEYLDR SFQANHVSKV TIFVSPYDF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards