Ankyrin repeat domain-containing protein 39 (ANKRD39)

About Ankyrin repeat domain-containing protein 39

Ankyrin repeat domain-containing protein 39 (ANKRD39) is a protein from Homo sapiens identified by UniProt accession Q53RE8, 183 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	Ankyrin repeat domain-containing protein 39
UniProt accession	Q53RE8
Gene	ANKRD39
Organism	Homo sapiens
Length	183 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

mathematical ability · score 0.26
calcium measurement · score 0.10
body height · score 0.09
vital capacity · score 0.05
systolic blood pressure · score 0.04
cortical thickness · score 0.04
sitting height measurement · score 0.03
forced expiratory volume · score 0.03
mean corpuscular volume · score 0.02
blood phosphate measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q53RE8-F1	alphafold	PREDICTED	84.03	—

Amino-acid sequence (183 residues)

MATPRPCADG PCCSHPSAVL GVQQTLEEMD FERGIWSAAL NGDLGRVKHL IQKAEDPSQP DSAGYTALHY ASRNGHYAVC QFLLESGAKC DAQTHGGATA LHRASYCGHT EIARLLLSHG SNPRVVDDDG MTSLHKAAER GHGDICSLLL QHSPALKAIR DRKARLACDL LPCNSDLRDL LSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards