About Proline-rich protein 30
Proline-rich protein 30 (PRR30) is a protein
from Homo sapiens identified by UniProt accession
Q53SZ7, 412 residues long.
MolForge cross-references it against 0 known binders and
3 disease associations.
Target properties
| Protein name | Proline-rich protein 30 |
| UniProt accession | Q53SZ7 |
| Gene | PRR30 |
| Organism | Homo sapiens |
| Length | 412 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (3)
Diseases linked to this target (Open Targets).
- bilirubin measurement · score 0.19
- breast carcinoma · score 0.04
- Azoospermia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q53SZ7-F1 | alphafold | PREDICTED | 58.73 | — |
Amino-acid sequence (412 residues)
MLPQNKDQVL PQTSVLPGRP TWGFSQLVDS SPHNLQPLSP HQGLPPSQPP FSSTQSRRPS SPPPASPSPG FQFGSCDSNS DFAPHPYSPS LPSSPTFFHQ NYLSLPRPRA SSPSNHWLYP SPPLTPSFSP SQPQNSSLPH SPCQSPSHPE ELHSSTLTSP GPSPPSHRLH SNRQTWRWHQ YRDTGSGSPG VVERCVPSEK DPAQFRDPGA LAQALVVQLG HRRIAHDLRL LLLQHLWLGR TGQAPVVEYP ICLVCLRPRS PSCPLPRYRT GPRLLAFPQL LPCVQGQESG PLRIGIGFGL RLPQGQARAL HLLPEKRPKE AGPQGKATQA CGHQLPASQP PAAQARADPV PGTPSQTRSF RSAGLQSPNS PRCFSGPPPR APKQVTTSLK PRPCPGPKRP VSLELILQKS SV
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